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The Glucagon-Like Peptide-1 Receptor Regulates Endogenous Glucose Production and Muscle Glucose Uptake Independent of Its Incretin Action

Glucagon-like peptide-1 (GLP-1) diminishes postmeal glucose excursions by enhancing insulin secretion via activation of the β-cell GLP-1 receptor (Glp1r). GLP-1 may also control glucose levels through mechanisms that are independent of this incretin effect. The hyperinsulinemic-euglycemic clamp (ins...

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Auteurs principaux: Ayala, Julio E., Bracy, Deanna P., James, Freyja D., Julien, Brianna M., Wasserman, David H., Drucker, Daniel J.
Format: Artigo
Langue:Inglês
Publié: The Endocrine Society 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654733/
https://ncbi.nlm.nih.gov/pubmed/19008308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0945
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