Intracoronary glucagon-like peptide 1 preferentially augments glucose uptake in ischemic myocardium independent of changes in coronary flow

We examined the acute dose-dependent effects of intracoronary glucagon-like peptide (GLP)-1 (7–36) on coronary vascular tone, cardiac contractile function and metabolism in normal and ischemic myocardium. Experiments were conducted in open chest, anesthetized dogs at coronary perfusion pressures (CP...

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Published in:Exp Biol Med (Maywood)
Main Authors: Moberly, Steven P, Berwick, Zachary C, Kohr, Meredith, Svendsen, Mark, Mather, Kieren J, Tune, Johnathan D
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141521/
https://ncbi.nlm.nih.gov/pubmed/22345302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2011.011288
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