Co-dependent functions of RSK2 and the apoptosis promoting factor, TIA-1, in stress granule assembly and cell survival

Stress granules aid cell survival in response to environmental stressors by acting as sites of translational repression. We report an unanticipated link between stress granules and the Ser/Thr kinase, RSK2. In stressed breast cells endogenous RSK2 co-localizes in granules with TIA-1 and poly-(A) bin...

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Détails bibliographiques
Auteurs principaux: Eisinger-Mathason, T.S. Karin, Andrade, Josefa, Groehler, Angela L., Clark, David E., Muratore-Schroeder, Tara L., Pasic, Lejla, Smith, Jeffrey A., Shabanowitz, Jeffrey, Hunt, Donald F., Macara, Ian G., Lannigan, Deborah A.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654589/
https://ncbi.nlm.nih.gov/pubmed/18775331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.06.025
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