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Stress Granule Assembly Is Mediated by Prion-like Aggregation of TIA-1

TIA-1 is an RNA binding protein that promotes the assembly of stress granules (SGs), discrete cytoplasmic inclusions into which stalled translation initiation complexes are dynamically recruited in cells subjected to environmental stress. The RNA recognition motifs of TIA-1 are linked to a glutamine...

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Detalhes bibliográficos
Main Authors: Gilks, Natalie, Kedersha, Nancy, Ayodele, Maranatha, Shen, Lily, Stoecklin, Georg, Dember, Laura M., Anderson, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC532018/
https://ncbi.nlm.nih.gov/pubmed/15371533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-08-0715
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