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Structural basis for catalysis of a tetrameric, class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis

Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), currently infects one third of the world’s population in its latent form. The emergence of multidrug resistant strains, MDR-TB and XDR-TB has highlighted the need for new pharmacological targets within M. tuberculosis. The Class I...

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Detalhes bibliográficos
Main Authors: Pegan, Scott D., Rukseree, Kamolchanok, Franzblau, Scott G., Mesecar, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654403/
https://ncbi.nlm.nih.gov/pubmed/19167403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.01.003
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