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A Noncompetitive Inhibitor for Mycobacterium tuberculosis's Class IIa Fructose 1,6-Bisphosphate Aldolase

[Image: see text] Class II fructose 1,6-bisphosphate aldolase (FBA) is an enzyme critical for bacterial, fungal, and protozoan glycolysis/gluconeogenesis. Importantly, humans lack this type of aldolase, having instead a class I FBA that is structurally and mechanistically distinct from class II FBAs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Capodagli, Glenn C., Sedhom, Wafik G., Jackson, Mary, Ahrendt, Kateri A., Pegan, Scott D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167715/
https://ncbi.nlm.nih.gov/pubmed/24325645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401022b
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