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CARDIAC OUTFLOW TRACT SEPTATION FAILURE IN Pax3-DEFICIENT EMBRYOS IS DUE TO p53-DEPENDENT REGULATION OF MIGRATING CARDIAC NEURAL CREST
During neural tube closure, Pax3 is required to inhibit p53-dependent apoptosis. Pax3 is also required for migration of cardiac neural crest (CNC) from the neural tube to the heart and septation of the primitive single cardiac outflow tract into the aorta and pulmonary arteries. Whether Pax3 is requ...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654333/ https://ncbi.nlm.nih.gov/pubmed/18672055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2008.07.003 |
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