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Neural crest–derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation

In mammals, the outflow tract (OFT) of the developing heart septates into the base of the pulmonary artery and aorta to guide deoxygenated right ventricular blood into the lungs and oxygenated left ventricular blood into the systemic circulation. Accordingly, defective OFT septation is a life-threat...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Plein, Alice, Calmont, Amélie, Fantin, Alessandro, Denti, Laura, Anderson, Naomi A., Scambler, Peter J., Ruhrberg, Christiana
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563681/
https://ncbi.nlm.nih.gov/pubmed/26053665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79668
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