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Neural crest–derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation
In mammals, the outflow tract (OFT) of the developing heart septates into the base of the pulmonary artery and aorta to guide deoxygenated right ventricular blood into the lungs and oxygenated left ventricular blood into the systemic circulation. Accordingly, defective OFT septation is a life-threat...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4563681/ https://ncbi.nlm.nih.gov/pubmed/26053665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79668 |
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