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Drop-the-Losers Design: Binomial Case

Drop-the-losers designs were introduced for normal distributions as a method of combining phase II and III clinical trials together under a single protocol with the purpose of more rapidly evaluating drugs by eliminating as much as possible the delays that typically occur between the two phases of c...

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Autori principali: Sill, Michael W., Sampson, Allan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654329/
https://ncbi.nlm.nih.gov/pubmed/20047003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csda.2008.07.031
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