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A multi-stage drop-the-losers design for multi-arm clinical trials

Multi-arm multi-stage trials can improve the efficiency of the drug development process when multiple new treatments are available for testing. A group-sequential approach can be used in order to design multi-arm multi-stage trials, using an extension to Dunnett’s multiple-testing procedure. The act...

詳細記述

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書誌詳細
出版年:Stat Methods Med Res
主要な著者: Wason, James, Stallard, Nigel, Bowden, Jack, Jennison, Christopher
フォーマット: Artigo
言語:Inglês
出版事項: SAGE Publications 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302074/
https://ncbi.nlm.nih.gov/pubmed/25228636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280214550759
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