High-Throughput Detection of Induced Mutations and Natural Variation Using KeyPoint™ Technology

Reverse genetics approaches rely on the detection of sequence alterations in target genes to identify allelic variants among mutant or natural populations. Current (pre-) screening methods such as TILLING and EcoTILLING are based on the detection of single base mismatches in heteroduplexes using end...

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Hlavní autoři: Rigola, Diana, van Oeveren, Jan, Janssen, Antoine, Bonné, Anita, Schneiders, Harrie, van der Poel, Hein J. A., van Orsouw, Nathalie J., Hogers, René C. J., de Both, Michiel T. J., van Eijk, Michiel J. T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654077/
https://ncbi.nlm.nih.gov/pubmed/19283079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004761
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