Complexity Reduction of Polymorphic Sequences (CRoPS™): A Novel Approach for Large-Scale Polymorphism Discovery in Complex Genomes

Application of single nucleotide polymorphisms (SNPs) is revolutionizing human bio-medical research. However, discovery of polymorphisms in low polymorphic species is still a challenging and costly endeavor, despite widespread availability of Sanger sequencing technology. We present CRoPS™ as a nove...

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Hlavní autoři: van Orsouw, Nathalie J., Hogers, René C. J., Janssen, Antoine, Yalcin, Feyruz, Snoeijers, Sandor, Verstege, Esther, Schneiders, Harrie, van der Poel, Hein, van Oeveren, Jan, Verstegen, Harold, van Eijk, Michiel J. T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048665/
https://ncbi.nlm.nih.gov/pubmed/18000544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001172
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