Complexity Reduction of Polymorphic Sequences (CRoPS™): A Novel Approach for Large-Scale Polymorphism Discovery in Complex Genomes

Application of single nucleotide polymorphisms (SNPs) is revolutionizing human bio-medical research. However, discovery of polymorphisms in low polymorphic species is still a challenging and costly endeavor, despite widespread availability of Sanger sequencing technology. We present CRoPS™ as a nove...

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Autori principali: van Orsouw, Nathalie J., Hogers, René C. J., Janssen, Antoine, Yalcin, Feyruz, Snoeijers, Sandor, Verstege, Esther, Schneiders, Harrie, van der Poel, Hein, van Oeveren, Jan, Verstegen, Harold, van Eijk, Michiel J. T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048665/
https://ncbi.nlm.nih.gov/pubmed/18000544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001172
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