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High-Throughput Detection of Induced Mutations and Natural Variation Using KeyPoint™ Technology
Reverse genetics approaches rely on the detection of sequence alterations in target genes to identify allelic variants among mutant or natural populations. Current (pre-) screening methods such as TILLING and EcoTILLING are based on the detection of single base mismatches in heteroduplexes using end...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654077/ https://ncbi.nlm.nih.gov/pubmed/19283079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004761 |
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