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Role of GLI2 Transcription Factor in Growth and Tumorigenicity of Prostate Cells

Aberrant activation of the Hedgehog (Hh) signaling pathway has been reported in various cancer types including prostate cancer. The GLI2 transcription factor is a primary mediator of Hh signaling. However, its relative contribution to development of prostate tumors is poorly understood. To establish...

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Detalhes bibliográficos
Main Authors: Thiyagarajan, Saravanan, Bhatia, Neehar, Reagan-Shaw, Shannon, Cozma, Diana, Thomas-Tikhonenko, Andrei, Ahmad, Nihal, Spiegelman, Vladimir S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653855/
https://ncbi.nlm.nih.gov/pubmed/18006803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-2015
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