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Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation
We analysed the effects of small interfering RNA (siRNA)-mediated silencing of Apollon, a member of the inhibitors of apoptosis protein family, on the proliferative potential and ability of human breast cancer cell lines to undergo apoptosis. In wild-type p53 ZR75.1 cells, Apollon knockdown resulted...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653776/ https://ncbi.nlm.nih.gov/pubmed/19223905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604927 |
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