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Overexpressed vs mutated Kras in murine fibroblasts: a molecular phenotyping study
Ras acts in signalling pathways regulating the activity of multiple cellular functions including cell proliferation, differentiation, and apoptosis. Amino-acid exchanges at position 12, 13, or 61 of the Kras gene convert the proto-oncogene into an activated oncogene. Until now, a direct comparison o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653730/ https://ncbi.nlm.nih.gov/pubmed/19190631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604882 |
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