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Centrosome Amplification Can Initiate Tumorigenesis in Flies
Centrosome amplification is a common feature of many cancer cells, and it has been previously proposed that centrosome amplification can drive genetic instability and so tumorigenesis. To test this hypothesis, we generated Drosophila lines that have extra centrosomes in ~60% of their somatic cells....
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653712/ https://ncbi.nlm.nih.gov/pubmed/18555779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.05.039 |
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