Discovery of Novel Hypermethylated Genes in Prostate Cancer Using Genomic CpG Island Microarrays

BACKGROUND: Promoter and 5′ end methylation regulation of tumour suppressor genes is a common feature of many cancers. Such occurrences often lead to the silencing of these key genes and thus they may contribute to the development of cancer, including prostate cancer. METHODOLOGY/PRINCIPAL FINDINGS:...

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Autori principali: Kron, Ken, Pethe, Vaijayanti, Briollais, Laurent, Sadikovic, Bekim, Ozcelik, Hilmi, Sunderji, Alia, Venkateswaran, Vasundara, Pinthus, Jehonathan, Fleshner, Neil, van der Kwast, Theodorus, Bapat, Bharati
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653233/
https://ncbi.nlm.nih.gov/pubmed/19283074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004830
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