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Chemical Probes that Competitively and Selectively Inhibit Stat3 Activation
Signal transducer and activator of transcription (Stat) 3 is an oncogene constitutively activated in many cancer systems where it contributes to carcinogenesis. To develop chemical probes that selectively target Stat3, we virtually screened 920,000 small drug-like compounds by docking each into the...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653189/ https://ncbi.nlm.nih.gov/pubmed/19274102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004783 |
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