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HUMAN PXR VARIANTS AND THEIR DIFFERENTIAL EFFECTS ON THE REGULATION OF HUMAN UDP-GLUCURONOSYLTRANSFERASE GENE EXPRESSION

The pregnane X receptor (PXR) has three known major transcript variants resulting from alternative splicing. The less well characterized variants T2 and T3 are identical to the well described variant T1 except for a 39-amino acid N-terminal extension in T2 and an internal 37-amino acid deletion in T...

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Detalhes bibliográficos
Main Authors: Gardner-Stephen, Dione, Heydel, Jean-Marie, Goyal, Amit, Lu, Yuan, Xie, Wen, Lindblom, Tim, Mackenzie, Peter, Radominska-Pandya, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652677/
https://ncbi.nlm.nih.gov/pubmed/14977869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.32.3.340
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