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A synthetic entry to pladienolide B and FD-895

Presented within are syntheses of the pladienolide B and FD-895 side-chains, as well as models of the essential ring-closing metathesis and Stille coupling that will be used to complete the total synthesis of both products. Several analogs of the pladienolide B side-chain were also prepared in order...

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Detalhes bibliográficos
Main Authors: Mandel, Alexander L., Jones, Brian D., La Clair, James J., Burkart, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652656/
https://ncbi.nlm.nih.gov/pubmed/17681759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.06.094
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