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KLF4 REGULATION IN INTESTINAL EPITHELIAL CELL MATURATION

The Krüppel-like factor 4 (KLF4) transcription factor suppresses tumorigenesis in gastrointestinal epithelium. Thus, its expression is decreased in gastric and colon cancers. Moreover, KLF4 regulates both differentiation and growth that is likely fundamental to its tumor suppressor activity. We diss...

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Bibliographic Details
Main Authors: Flandez, M., Guilmeau, S., Blache, P., Augenlicht, L.H.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652355/
https://ncbi.nlm.nih.gov/pubmed/18977346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.10.004
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