KLF4 REGULATION IN INTESTINAL EPITHELIAL CELL MATURATION

The Krüppel-like factor 4 (KLF4) transcription factor suppresses tumorigenesis in gastrointestinal epithelium. Thus, its expression is decreased in gastric and colon cancers. Moreover, KLF4 regulates both differentiation and growth that is likely fundamental to its tumor suppressor activity. We diss...

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Bibliografiske detaljer
Main Authors: Flandez, M., Guilmeau, S., Blache, P., Augenlicht, L.H.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652355/
https://ncbi.nlm.nih.gov/pubmed/18977346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.10.004
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