Suberoylanilide Hydroxamic Acid Reactivates HIV from Latently Infected Cells

Human immunodeficiency virus (HIV) persists in a latent form in infected individuals treated effectively with highly active antiretroviral therapy (HAART). In part, these latent proviruses account for the rebound in viral replication observed after treatment interruption. A major therapeutic challen...

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Hlavní autoři: Contreras, Xavier, Schweneker, Marc, Chen, Ching-Shih, McCune, Joseph M., Deeks, Steven G., Martin, Jeffrey, Peterlin, B. Matija
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Transcription, Chromatin, and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652322/
https://ncbi.nlm.nih.gov/pubmed/19136668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807898200
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