Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy

Microarrays are frequently used to profile genome-wide copy number (CN) aberrations. While generally robust for detecting CN variants in germline DNA, the methods used to derive CN from signal intensity values have been suboptimal when applied to cancer genomes. The complexity of genomic aberrations...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Attiyeh, Edward F., Diskin, Sharon J., Attiyeh, Marc A., Mossé, Yaël P., Hou, Cuiping, Jackson, Eric M., Kim, Cecilia, Glessner, Joseph, Hakonarson, Hakon, Biegel, Jaclyn A., Maris, John M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2009
Aiheet:
Methods
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652209/
https://ncbi.nlm.nih.gov/pubmed/19141597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.075671.107
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