Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy

Microarrays are frequently used to profile genome-wide copy number (CN) aberrations. While generally robust for detecting CN variants in germline DNA, the methods used to derive CN from signal intensity values have been suboptimal when applied to cancer genomes. The complexity of genomic aberrations...

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Bibliografski detalji
Glavni autori: Attiyeh, Edward F., Diskin, Sharon J., Attiyeh, Marc A., Mossé, Yaël P., Hou, Cuiping, Jackson, Eric M., Kim, Cecilia, Glessner, Joseph, Hakonarson, Hakon, Biegel, Jaclyn A., Maris, John M.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2009
Teme:
Methods
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652209/
https://ncbi.nlm.nih.gov/pubmed/19141597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.075671.107
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