Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy

Microarrays are frequently used to profile genome-wide copy number (CN) aberrations. While generally robust for detecting CN variants in germline DNA, the methods used to derive CN from signal intensity values have been suboptimal when applied to cancer genomes. The complexity of genomic aberrations...

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Detalhes bibliográficos
Main Authors: Attiyeh, Edward F., Diskin, Sharon J., Attiyeh, Marc A., Mossé, Yaël P., Hou, Cuiping, Jackson, Eric M., Kim, Cecilia, Glessner, Joseph, Hakonarson, Hakon, Biegel, Jaclyn A., Maris, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
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Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652209/
https://ncbi.nlm.nih.gov/pubmed/19141597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.075671.107
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