Chromosomal instability mediated by non-B DNA: Cruciform conformation and not DNA sequence is responsible for recurrent translocation in humans

Chromosomal aberrations have been thought to be random events. However, recent findings introduce a new paradigm in which certain DNA segments have the potential to adopt unusual conformations that lead to genomic instability and nonrandom chromosomal rearrangement. One of the best-studied examples...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Inagaki, Hidehito, Ohye, Tamae, Kogo, Hiroshi, Kato, Takema, Bolor, Hasbaira, Taniguchi, Mariko, Shaikh, Tamim H., Emanuel, Beverly S., Kurahashi, Hiroki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2009
Gaiak:
Letter
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652202/
https://ncbi.nlm.nih.gov/pubmed/18997000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.079244.108
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak