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Cruciform DNA Structure Underlies the Etiology for Palindrome-mediated Human Chromosomal Translocations
There is accumulating evidence to suggest that palindromic AT-rich repeats (PATRRs) represent hot spots of double-strand breakage that lead to recurrent chromosomal translocations in humans. As a mechanism for such rearrangements, we proposed that the PATRR forms a cruciform structure that is the so...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810964/ https://ncbi.nlm.nih.gov/pubmed/15208332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M400354200 |
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