Local energetic regulation of sarcoplasmic and myosin ATPase is differently impaired in rats with heart failure

Local control of ATP/ADP ratio is essential for efficient functioning of cellular ATPases. Since creatine kinase (CK) activity and mitochondrial content are reduced in heart failure (HF), and cardiomyocyte ultrastructure is altered, we hypothesized that these changes may affect the local energetic c...

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Bibliographische Detailangaben
Hauptverfasser: Joubert, Frederic, Wilding, James R, Fortin, Dominique, Domergue-Dupont, Valérie, Novotova, Marta, Ventura-Clapier, Renée, Veksler, Vladimir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2008
Schlagworte:
Cardiovascular
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652147/
https://ncbi.nlm.nih.gov/pubmed/18787038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.157677
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