Local energetic regulation of sarcoplasmic and myosin ATPase is differently impaired in rats with heart failure

Local control of ATP/ADP ratio is essential for efficient functioning of cellular ATPases. Since creatine kinase (CK) activity and mitochondrial content are reduced in heart failure (HF), and cardiomyocyte ultrastructure is altered, we hypothesized that these changes may affect the local energetic c...

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Detalhes bibliográficos
Main Authors: Joubert, Frederic, Wilding, James R, Fortin, Dominique, Domergue-Dupont, Valérie, Novotova, Marta, Ventura-Clapier, Renée, Veksler, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652147/
https://ncbi.nlm.nih.gov/pubmed/18787038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.157677
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