Local energetic regulation of sarcoplasmic and myosin ATPase is differently impaired in rats with heart failure

Local control of ATP/ADP ratio is essential for efficient functioning of cellular ATPases. Since creatine kinase (CK) activity and mitochondrial content are reduced in heart failure (HF), and cardiomyocyte ultrastructure is altered, we hypothesized that these changes may affect the local energetic c...

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Main Authors: Joubert, Frederic, Wilding, James R, Fortin, Dominique, Domergue-Dupont, Valérie, Novotova, Marta, Ventura-Clapier, Renée, Veksler, Vladimir
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2008
Teme:
Cardiovascular
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652147/
https://ncbi.nlm.nih.gov/pubmed/18787038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.157677
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