Altered energy transfer from mitochondria to sarcoplasmic reticulum after cytoarchitectural perturbations in mice hearts

Sarcoplasmic reticulum (SR) calcium pump function requires a high local ATP/ADP ratio, which can be maintained by direct nucleotide channelling from mitochondria, and by SR-bound creatine kinase (CK)-catalysed phosphate-transfer from phosphocreatine. We hypothesized that SR calcium uptake supported...

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Bibliographische Detailangaben
Hauptverfasser: Wilding, James R, Joubert, Frédéric, de Araujo, Carla, Fortin, Dominique, Novotova, Marta, Veksler, Vladimir, Ventura-Clapier, Renée
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2006
Schlagworte:
Cardiovascular
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1819422/
https://ncbi.nlm.nih.gov/pubmed/16740607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.114116
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