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SAP-controlled T-B cell interactions underlie germinal centre formation

Generation of long-term antibody-mediated immunity depends on the germinal centre (GC) reaction, which requires cooperation between antigen-specific T and B lymphocytes. In the human X-linked lymphoproliferative disease and its gene-targeted mouse model, loss-of-function mutations in signalling lymp...

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Detalhes bibliográficos
Main Authors: Qi, Hai, Cannons, Jennifer L., Klauschen, Frederick, Schwartzberg, Pamela L., Germain, Ronald N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652134/
https://ncbi.nlm.nih.gov/pubmed/18843362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07345
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