Optimal Germinal Center Responses Require A Multi-stage T:B Cell Adhesion Process Involving Integrins, SLAM-associated protein and CD84

CD4(+) T cells deficient in signaling lymphocyte activation molecule (SLAM)-associated protein (SAP) exhibit a selective impairment in adhesion to antigen presenting B cells but not dendritic cells (DC), resulting in defective germinal center formation. However, the nature of this selective adhesion...

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Bibliographische Detailangaben
Hauptverfasser: Cannons, Jennifer L., Qi, Hai, Lu, Kristina T., Ghai, Mala, Gomez-Rodriguez, Julio, Cheng, Jun, Wakeland, Edward K., Germain, Ronald N., Schwartzberg, Pamela L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830297/
https://ncbi.nlm.nih.gov/pubmed/20153220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.01.010
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