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Structural rearrangements linked to global folding pathways of the Azoarcus group I ribozyme
Stable RNAs must fold into specific three-dimensional structures to be biologically active, yet many RNAs form metastable structures that compete with the native state. Our previous time-resolved footprinting experiments showed that Azoarcus group I ribozyme forms its tertiary structure rapidly (τ &...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651841/ https://ncbi.nlm.nih.gov/pubmed/19154736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.12.075 |
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