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Structural rearrangements linked to global folding pathways of the Azoarcus group I ribozyme

Stable RNAs must fold into specific three-dimensional structures to be biologically active, yet many RNAs form metastable structures that compete with the native state. Our previous time-resolved footprinting experiments showed that Azoarcus group I ribozyme forms its tertiary structure rapidly (τ &...

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Detalhes bibliográficos
Main Authors: Chauhan, Seema, Behrouzi, Reza, Rangan, Prashanth, Woodson, Sarah A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651841/
https://ncbi.nlm.nih.gov/pubmed/19154736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.12.075
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