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A genetic screen for components of the mammalian RNA interference pathway in Bloom-deficient mouse embryonic stem cells

Genetic screens performed in model organisms have helped identify key components of the RNA interference (RNAi) pathway. Recessive genetic screens have recently become feasible through the use of mouse embryonic stem (ES) cells that are Bloom's syndrome protein (Blm) deficient. Here, we develop...

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Bibliografiske detaljer
Main Authors: Trombly, Melanie I., Su, Hong, Wang, Xiaozhong
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651804/
https://ncbi.nlm.nih.gov/pubmed/19223321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp019
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