Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency

Approximately 3,500 mammalian genes are predicted to be secreted or single-pass transmembrane proteins. The function of the majority of these genes is still unknown, and a number of the encoded proteins might find use as new therapeutic agents themselves or as targets for small molecule or antibody...

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Bibliografiska uppgifter
Huvudupphovsmän: Gonzalez, Rodolfo, Jennings, Lori L., Knuth, Mark, Orth, Anthony P., Klock, Heath E., Ou, Weija, Feuerhelm, Julie, Hull, Mitchell V., Koesema, Eric, Wang, Yuping, Zhang, Jia, Wu, Chunlei, Cho, Charles Y., Su, Andrew I., Batalov, Serge, Chen, Hong, Johnson, Kristen, Laffitte, Bryan, Nguyen, Deborah G., Snyder, Evan Y., Schultz, Peter G., Harris, Jennifer L., Lesley, Scott A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840467/
https://ncbi.nlm.nih.gov/pubmed/20133595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914019107
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