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Challenges of modeling complex neuropsychiatric disorders with human induced pluripotent stem cells (hiPSCs): From “disease-in-a-dish” to personalized drug discovery
Identifying the molecular and cellular basis of complex neuropsychiatric disorders (cNPDs) has been limited by the inaccessibility of central neurons, variability within broad diagnostic classifications, and the interplay of genetic and environmental factors. Recent work utilizing neuronally differe...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428145/ https://ncbi.nlm.nih.gov/pubmed/21723195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2011.05.007 |
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