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A genetic screen for components of the mammalian RNA interference pathway in Bloom-deficient mouse embryonic stem cells
Genetic screens performed in model organisms have helped identify key components of the RNA interference (RNAi) pathway. Recessive genetic screens have recently become feasible through the use of mouse embryonic stem (ES) cells that are Bloom's syndrome protein (Blm) deficient. Here, we develop...
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Главные авторы: | , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Oxford University Press
2009
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651804/ https://ncbi.nlm.nih.gov/pubmed/19223321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp019 |
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