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A genetic screen for components of the mammalian RNA interference pathway in Bloom-deficient mouse embryonic stem cells

Genetic screens performed in model organisms have helped identify key components of the RNA interference (RNAi) pathway. Recessive genetic screens have recently become feasible through the use of mouse embryonic stem (ES) cells that are Bloom's syndrome protein (Blm) deficient. Here, we develop...

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Библиографические подробности
Главные авторы: Trombly, Melanie I., Su, Hong, Wang, Xiaozhong
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651804/
https://ncbi.nlm.nih.gov/pubmed/19223321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp019
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