Mechanism of DNA flexibility enhancement by HMGB proteins

The mechanism by which sequence non-specific DNA-binding proteins enhance DNA flexibility is studied by examining complexes of double-stranded DNA with the high mobility group type B proteins HMGB2 (Box A) and HMGB1 (Box A+B) using atomic force microscopy. DNA end-to-end distances and local DNA bend...

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Main Authors: Zhang, Jingyun, McCauley, Micah J., Maher, L. James, Williams, Mark C., Israeloff, N. E.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651801/
https://ncbi.nlm.nih.gov/pubmed/19129233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1011
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