Single-molecule kinetics reveal microscopic mechanism by which High-Mobility Group B proteins alter DNA flexibility

Eukaryotic High-Mobility Group B (HMGB) proteins alter DNA elasticity while facilitating transcription, replication and DNA repair. We developed a new single-molecule method to probe non-specific DNA interactions for two HMGB homologs: the human HMGB2 box A domain and yeast Nhp6Ap, along with chimer...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: McCauley, Micah J., Rueter, Emily M., Rouzina, Ioulia, Maher, L. James, Williams, Mark C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2013
Aiheet:
Gene Regulation, Chromatin and Epigenetics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592474/
https://ncbi.nlm.nih.gov/pubmed/23143110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1031
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia