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Single-molecule kinetics reveal microscopic mechanism by which High-Mobility Group B proteins alter DNA flexibility
Eukaryotic High-Mobility Group B (HMGB) proteins alter DNA elasticity while facilitating transcription, replication and DNA repair. We developed a new single-molecule method to probe non-specific DNA interactions for two HMGB homologs: the human HMGB2 box A domain and yeast Nhp6Ap, along with chimer...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3592474/ https://ncbi.nlm.nih.gov/pubmed/23143110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1031 |
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