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A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU)

Xeroderma pigmentosum (XP) is an autosomal recessive genetic disorder. Afflicted patients show extreme sun-sensitivity and skin cancer predisposition. XP is in most cases associated with deficient nucleotide excision repair (NER), which is the process responsible for removing photolesions from DNA....

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Autors principals: Limsirichaikul, Siripan, Niimi, Atsuko, Fawcett, Heather, Lehmann, Alan, Yamashita, Shunichi, Ogi, Tomoo
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651789/
https://ncbi.nlm.nih.gov/pubmed/19179371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp023
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