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Concurrent Binding of Complexin and Synaptotagmin to Liposome-Embedded SNARE Complexes

[Image: see text] Synaptotagmin and complexin regulate SNARE-mediated synaptic vesicle exocytosis. It has been proposed that complexin clamps membrane fusion and that Ca(2+)-synaptotagmin displaces complexin from SNARE complexes to relieve this clamping activity. Using a reconstituted system, we dem...

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Main Authors: Chicka, Michael C., Chapman, Edwin R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2009
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651691/
https://ncbi.nlm.nih.gov/pubmed/19128031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801962d
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