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The core trisaccharide of an N-linked glycoprotein intrinsically accelerates folding and enhances stability

The folding energetics of the mono-N-glycosylated adhesion domain of the human immune cell receptor cluster of differentiation 2 (hCD2ad) were studied systematically to understand the influence of the N-glycan on the folding energy landscape. Fully elaborated N-glycan structures accelerate folding b...

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Detalhes bibliográficos
Main Authors: Hanson, Sarah R., Culyba, Elizabeth K., Hsu, Tsui-Ling, Wong, Chi-Huey, Kelly, Jeffery W., Powers, Evan T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651298/
https://ncbi.nlm.nih.gov/pubmed/19204290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810318105
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