A role for Orai in TRPC-mediated Ca(2+) entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca(2+) entry

TRPC and Orai proteins have both been proposed to form Ca(2+)-selective, store-operated calcium entry (SOCE) channels that are activated by store-depletion with Ca(2+) chelators or calcium pump inhibitors. In contrast, only TRPC proteins have been proposed to form nonselective receptor-operated calc...

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Bibliographic Details
Main Authors: Liao, Yanhong, Plummer, Nicholas W., George, Margaret D., Abramowitz, Joel, Zhu, Michael Xi, Birnbaumer, Lutz
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651283/
https://ncbi.nlm.nih.gov/pubmed/19221033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813346106
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