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Rad52 promotes second-end DNA capture in double-stranded break repair to form complement-stabilized joint molecules

Saccharomyces cerevisiae Rad52 performs multiple functions during the recombinational repair of double-stranded DNA (dsDNA) breaks (DSBs). It mediates assembly of Rad51 onto single-stranded DNA (ssDNA) that is complexed with replication protein A (RPA); the resulting nucleoprotein filament pairs wit...

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Detalles Bibliográficos
Main Authors: Nimonkar, Amitabh V., Sica, R. Alejandro, Kowalczykowski, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651264/
https://ncbi.nlm.nih.gov/pubmed/19204284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813247106
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