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A mitochondrial DNA mutation linked to colon cancer results in proton leaks in cytochrome c oxidase

An increasing number of cancer types have been found to be linked to specific mutations in the mitochondrial DNA, which result in specific structural changes of the respiratory enzyme complexes. In this study, we have investigated the effect of 2 such mutations identified in colon cancer patients, l...

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Main Authors: Namslauer, Ida, Brzezinski, Peter
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651238/
https://ncbi.nlm.nih.gov/pubmed/19218458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811450106
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