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A mitochondrial DNA mutation linked to colon cancer results in proton leaks in cytochrome c oxidase

An increasing number of cancer types have been found to be linked to specific mutations in the mitochondrial DNA, which result in specific structural changes of the respiratory enzyme complexes. In this study, we have investigated the effect of 2 such mutations identified in colon cancer patients, l...

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Bibliografische gegevens
Hoofdauteurs: Namslauer, Ida, Brzezinski, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651238/
https://ncbi.nlm.nih.gov/pubmed/19218458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811450106
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